Platelets and restenosis
نویسندگان
چکیده
منابع مشابه
Platelets and restenosis.
Restenosis is currently the major limitation of percutaneous transluminal coronary angioplasty (PTCA). Factors such as elastic recoil, migration of vascular smooth muscle cells from media to intima, neointimal proliferation and vascular remodeling underly the restenotic process. Presently there is no effective therapy available for restenosis. The role of platelets in the development of thrombo...
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Adhesive and signaling interactions between endothelial cells and leukocytes are key mechanisms that mediate both targeting of the blood cells to specific sites and information transfer that results in change in their phenotypes and function.1 These events are beneficial in defense against microbes and wound surveillance and repair; however, in dysregulated inflammatory conditions such as ather...
متن کاملUbiquitin, Proteasome, and Restenosis
In the present issue of Circulation, Meiners and his colleagues1 show that local application of a proteasome inhibitor resulted in significant inhibition of intimal hyperplasia in a balloon injury model in rat carotid artery. This report is of interest because it identifies a novel target for the treatment of restenosis and introduces a rapidly developing field in basic science to cardiovascula...
متن کاملThe source of HLA molecules on platelets: Does platelets adsorb soluble HLA molecules from their environment?
Background: The origin and function of human leukocyte antigen (HLA) class I molecules on platelets are still highly arguable. Given the differences in the results of the previous studies in this regard, the lack of research in recent years, and the clinical importance of HLA class I molecules, the absorption capacity of platelets for soluble HLA class I molecules was studied in this investigat...
متن کاملGenes, matrix, and restenosis.
Genes, Matrix, and Restenosis Print ISSN: 1079-5642. Online ISSN: 1524-4636 Copyright © 2000 American Heart Association, Inc. All rights reserved. Greenville Avenue, Dallas, TX 75231 is published by the American Heart Association, 7272 Arteriosclerosis, Thrombosis, and Vascular Biology doi: 10.1161/01.ATV.20.10.2173 2000;20:2173-2174 Arterioscler Thromb Vasc Biol. http://atvb.ahajournals.org/co...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2000
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(99)00596-3